HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: LG3BP (Q08380)
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)
Gene: LGALS3BP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 585
+	Hs
		995393 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		312588 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		229108 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KLH20_HUMAN (119-506): 4.11e-104: 328: 14.25
+	Hs
		227811 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KLH17_HUMAN (135-456): 1.12e-89: 291: 15.29
+	Hs
		226113 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KLH18_HUMAN (116-439): 1.41e-89: 289: 14.89
+	Hs
		228211 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KLHL6_HUMAN (139-506): 2.49e-85: 279: 15.31
+	Hs
		227421 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		1120832 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KLH12_HUMAN (127-458): 1e-96: 308: 13.95
+	Hs
		307235 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KLHL2_HUMAN (107-456): 4.95e-91: 293: 12.39
+	Hs
		1377911 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		IPP_HUMAN (117-457): 1.28e-86: 281: 12.97
+	Hs
		1350372 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KLHL9_HUMAN (122-516): 1.03e-83: 275: 14.87
+	Hs
		1350485 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		1121512 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KLH26_HUMAN (128-436): 3.37e-76: 255: 16.29
+	Hs
		475860 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KLH12_HUMAN (127-458): 1e-96: 308: 13.95
+	Hs
		476473 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KLH28_HUMAN (119-506): 3.21e-87: 283: 13.80
+	Hs
		476498 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		475742 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		1219361 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		LOXL4_HUMAN (15-104): 1.31e-09: 63.2: 25.66
+	Hs
		476518 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DMBT1_HUMAN (19-134): 8.49e-49: 185: 51.72
+	Hs
		476626 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82