HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: KDM3B (Q7LBC6)
Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B)
Gene: KDM3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1761
+	Hs
		475970 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KDM3B_HUMAN (1-1761): 0: 1698: 100.00
+	At
		86043 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		JMJ26_ARATH (1287-1752): 0: 615: 29.72
+	Hs
		228019 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		AGRG4_HUMAN (206-1400): 4.02e-42: 173: 10.69
+	Hs
		228669 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TARA_HUMAN (266-1269): 4.06e-27: 123: 9.73
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (248-1378): 1.55e-21: 105: 9.18
+	Hs
		227460 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MDC1_HUMAN (370-967): 2.07e-12: 75: 10.97
+	Hs
		226688 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NU214_HUMAN (282-882): 4.35e-11: 70.4: 12.79
+	Hs
		228101 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KMT2C_HUMAN (317-929): 8.49e-11: 69.7: 12.05
+	Hs
		228767 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAGE1_HUMAN (536-909): 7.4e-11: 69.7: 17.59
+	Hs
		475943 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OTOG_HUMAN (219-897): 1.57e-39: 164: 10.60
+	At
		1092118 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LIE8_ARATH (394-1376): 1.74e-10: 68.6: 7.63