HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ABCF1 (Q8NE71)
ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)
Gene: ABCF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 845
+	Hs
		228847 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ABCF3_HUMAN (609-845): 6.82e-31: 131: 18.48
+	Hs
		228974 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ABCF2_HUMAN (636-843): 3.58e-26: 116: 18.38
+	Sc
		477108 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		EF3A_YEAST (387-559): 2.43e-15: 82.9: 19.32
+	Sc
		477401 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		EF3B_YEAST (399-558): 1.33e-14: 80.2: 21.21
+	At
		1092037 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB1F_ARATH (636-843): 1.2e-28: 124: 20.43
+	At
		1092234 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AB4F_ARATH (636-838): 1.71e-25: 114: 22.63