Protein: S22A6
Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1)

Gene: S22A6, SLC22A6
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q4U2R8

Gene Ontology (top 5):
GO:0005452 - solute:inorganic anion antiporter activity
GO:0005886 - plasma membrane
GO:0005901 - caveola
GO:0006820 - monoatomic anion transport
GO:0008514 - organic anion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

732821

GLPK
Glycerol kinase

2

1

High-throughput

0.628

High

895354

S26A2
Sulfate transporter

2

4

High-throughput

0.628

High

1063049

S20A2
Sodium-dependent phosphate transporter 2

2

2

High-throughput

0.628

High

1196224

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

9

High-throughput

0.604

High

1196209

APBP2
Amyloid protein-binding protein 2

2

1

High-throughput

0.584

High

1196193

MTX3
Metaxin-3

2

4

High-throughput

0.574

High

1196194

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

2

9

High-throughput

0.574

High

1196195

MBOA5
Lysophospholipid acyltransferase 5

2

6

High-throughput

0.574

High

1196204

MCU
Calcium uniporter protein, mitochondrial

2

1

High-throughput

0.574

High

1196205

ATLA2
Atlastin-2

2

4

High-throughput

0.574

High

1196206

SFXN5
Sideroflexin-5

2

2

High-throughput

0.574

High

1196210

S2546
Mitochondrial outer membrane protein SLC25A46

2

5

High-throughput

0.574

High

1196212

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

2

9

High-throughput

0.574

High

1196214

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

2

9

High-throughput

0.574

High

1196218

S38A7
Sodium-coupled neutral amino acid transporter 7

2

1

High-throughput

0.574

High

689946

IL3RA
Interleukin-3 receptor subunit alpha

1

1

High-throughput

0.536

High

1196201

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.536

High

325553

YIF1A
Protein YIF1A

1

2

High-throughput

0.489

High

1116360

RAB32
Ras-related protein Rab-32

1

4

High-throughput

0.489

High

1196200

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

1

High-throughput

0.489

High

1196207

CHPT1
Cholinephosphotransferase 1

1

3

High-throughput

0.489

High

1196221

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.489

High

422238

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

861635

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

8

Small-scale

0.479

High

1196211

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

8

Small-scale

0.479

High

373968

RASN
GTPase NRas

1

5

High-throughput

0.445

High

418677

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

6

High-throughput

0.445

High

475977

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

6

High-throughput

0.445

High

564830

NCAM1
Neural cell adhesion molecule 1

1

3

High-throughput

0.445

High

609697

LEG3
Galectin-3

1

4

High-throughput

0.445

High

641188

FGFR2
Fibroblast growth factor receptor 2

1

5

High-throughput

0.445

High

698721

CALX
Calnexin

1

9

High-throughput

0.445

High

719935

HMOX2
Heme oxygenase 2

1

2

High-throughput

0.445

High

959337

RAP1B
Ras-related protein Rap-1b

1

7

High-throughput

0.445

High

1086001

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

High-throughput

0.445

High

1101732

PTK7
Inactive tyrosine-protein kinase 7

1

2

High-throughput

0.445

High

1122613

MLEC
Malectin

1

1

High-throughput

0.445

High

1196199

KTN1
Kinectin

1

1

High-throughput

0.445

High

1196203

AT11C
Phospholipid-transporting ATPase IG

1

5

High-throughput

0.445

High

1196213

RNF5
E3 ubiquitin-protein ligase RNF5

1

8

High-throughput

0.445

High

1196216

CPVL
Probable serine carboxypeptidase CPVL

1

3

High-throughput

0.445

High

1196219

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

5

High-throughput

0.445

High

1196220

MDFIC
MyoD family inhibitor domain-containing protein

1

1

High-throughput

0.445

High

367592

CAH2
Carbonic anhydrase 2

1

0

High-throughput

0.426

High

565926

EF2
Elongation factor 2

1

0

High-throughput

0.426

High

1196208

NICA
Nicastrin

1

0

High-throughput

0.426

High

1196222

NCKX2
Sodium/potassium/calcium exchanger 2

1

0

High-throughput

0.426

High

170789

CLGN
Calmegin

1

9

High-throughput

0.407

High

214212

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

2

High-throughput

0.407

High

1083173

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

2

High-throughput

0.407

High

1196202

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

3

High-throughput

0.407

High

1196215

XPO4
Exportin-4

1

3

High-throughput

0.407

High

1196217

TMX1
Thioredoxin-related transmembrane protein 1

1

6

High-throughput

0.407

High

1196223

CCPG1
Cell cycle progression protein 1

1

6

High-throughput

0.407

High

1196197

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

0

High-throughput

0.328

High

655219

SFPQ
Splicing factor, proline- and glutamine-rich

1

0

High-throughput

0.232

Low

1196196

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.232

Low

1196198

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025