HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: HNRL1 (Q9BUJ2)
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5)
Gene: HNRNPUL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 856
+	Hs
		227189 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Hs
		227608 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRL2_HUMAN (1-707): 0: 587: 38.67
+	Hs
		312655 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRL1_HUMAN (1-856): 0: 768: 100.00
+	Hs
		312575 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Hs
		475638 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		HNRPU_HUMAN (1-701): 0: 662: 40.41
+	Hs
		227529 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RYR3_HUMAN (115-499): 1.45e-81: 290: 14.22
+	Hs
		228217 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		228437 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RANB9_HUMAN (142-503): 1.14e-67: 241: 18.90
+	Hs
		227819 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBP10_HUMAN (146-503): 3.04e-61: 220: 16.80
+	Hs
		227742 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RN123_HUMAN (243-412): 6.53e-44: 174: 26.86
+	Hs
		1266160 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		DDX1_HUMAN (141-512): 9.29e-85: 288: 21.91
+	Hs
		476244 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RANB9_HUMAN (142-503): 1.14e-67: 241: 18.90
+	Hs
		475902 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RN123_HUMAN (243-412): 6.53e-44: 174: 26.86