HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ARL6 (Q9H0F7)
ADP-ribosylation factor-like protein 6 (Bardet-Biedl syndrome 3 protein)
Gene: ARL6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 186
+	Hs
		227167 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ARF5_HUMAN (1-184): 1.94e-72: 218: 35.87
+	Hs
		226471 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ARF4_HUMAN (1-184): 8.68e-72: 216: 38.71
+	Hs
		227038 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ARF3_HUMAN (1-185): 3.38e-65: 199: 40.64
+	Hs
		228651 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RAB1B_HUMAN (10-185): 4.88e-64: 197: 17.22
+	Hs
		227033 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RAB14_HUMAN (13-184): 9.82e-60: 187: 15.91
+	Hs
		918975 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		RAB1A_HUMAN (7-185): 2.79e-65: 200: 17.49
+	Zm
		43106 A0A1D6PFP9_MAIZE (202-461): 2.58e-61: 214: 23.16		B4FIX8_MAIZE (1-184): 4.64e-65: 199: 41.30
+	Sc
		350834 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		YPT1_YEAST (10-186): 4.07e-60: 187: 17.68
+	At
		1092212 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LYJ3_ARATH (1-184): 5.49e-74: 222: 41.40
+	Sc
		477325 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		ARF3_YEAST (5-185): 3.49e-40: 136: 40.76
+	Hs
		475624 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ARF1_HUMAN (1-185): 1.03e-64: 198: 40.11
+	At
		656930 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RAD2A_ARATH (10-185): 3.22e-65: 200: 15.56
+	At
		1092235 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9M1P5_ARATH (1-184): 5.01e-65: 199: 40.86
+	At
		734432 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ARF1_ARATH (1-184): 2.94e-65: 199: 40.86
+	At
		483049 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ARF2B_ARATH (1-184): 1.19e-64: 198: 40.86
+	At
		1091637 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RAB1B_ARATH (13-184): 1.91e-60: 188: 15.91
+	At
		955321 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RAB1C_ARATH (13-184): 2.26e-59: 186: 15.91
+	Zm
		24708 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		B4FNJ6_MAIZE (14-186): 5.06e-61: 190: 14.12