HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: TF3C3 (Q9Y5Q9)
General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)
Gene: GTF3C3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 886
+	Hs
		1219402 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		TF3C3_HUMAN (1-886): 1.1e-146: 457: 100.00
+	Hs
		476643 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		TF3C3_HUMAN (1-886): 1.1e-146: 457: 100.00
+	Hs
		228427 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		BBS4_HUMAN (89-481): 9.06e-26: 114: 15.48
+	Hs
		174471 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		OGT1_HUMAN (698-886): 2.34e-17: 89.3: 12.96
+	Hs
		228611 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CRNL1_HUMAN (306-760): 3.03e-16: 85.8: 8.77
+	Hs
		227803 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CTR9_HUMAN (25-542): 4.17e-16: 85.4: 12.81
+	Hs
		227849 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TMTC3_HUMAN (721-886): 7.6e-14: 77.7: 12.87
+	Hs
		227343 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DNJC3_HUMAN (424-766): 1.1e-10: 67.2: 15.32
+	Hs
		226116 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRP6_HUMAN (6-259): 5.65e-10: 65.4: 10.21
+	Dm
		1180619 PRKN_DROME (1-463): 3.5e-106: 325: 42.19		Q7KJA9_DROME (10-320): 1.31e-33: 141: 11.95
+	Hs
		227777 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NAA16_HUMAN (416-886): 9.34e-09: 61.2: 10.42
+	Dm
		284375 ARI2_DROME (228-464): 7.29e-69: 229: 20.92		Q7KJA9_DROME (10-320): 1.31e-33: 141: 11.95
+	Hs
		174509 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		OGT1_HUMAN (698-886): 2.34e-17: 89.3: 12.96
+	Hs
		476163 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		TTC28_HUMAN (39-684): 2.84e-38: 157: 9.68
+	Hs
		174570 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OGT1_HUMAN (698-886): 2.34e-17: 89.3: 12.96
+	Hs
		475702 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DNJC3_HUMAN (424-766): 1.1e-10: 67.2: 15.32