Protein: CHSS3
Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3)

Gene: CHSS3, CHSY3
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q70JA7

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0032580 - Golgi cisterna membrane
GO:0046872 - metal ion binding
GO:0047238 - glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
GO:0050510 - N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1258449

CHSS1
Chondroitin sulfate synthase 1

2

11

High-throughput

0.628

High

1258460

GOLP3
Golgi phosphoprotein 3

2

2

High-throughput

0.628

High

1258465

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

1

High-throughput

0.628

High

1258467

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

5

High-throughput

0.628

High

154837

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

3

4

High-throughput

0.609

High

1042638

UPAR
Urokinase plasminogen activator surface receptor

3

1

High-throughput

0.609

High

1101364

SG2A2
Mammaglobin-A

2

7

High-throughput

0.574

High

1258458

SC65
Endoplasmic reticulum protein SC65

2

1

High-throughput

0.574

High

1258462

RMND1
Required for meiotic nuclear division protein 1 homolog

2

1

High-throughput

0.574

High

976826

LCN6
Epididymal-specific lipocalin-6

2

7

High-throughput

0.549

High

1258454

MYBPP
MYCBP-associated protein

2

2

High-throughput

0.549

High

1258456

CA054
Uncharacterized protein C1orf54

2

8

High-throughput

0.549

High

755410

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

1

High-throughput

0.536

High

1258450

CHSS2
Chondroitin sulfate synthase 2

1

10

High-throughput

0.536

High

1258464

CHPF2
Chondroitin sulfate glucuronyltransferase

1

10

High-throughput

0.536

High

133865

FOXN3
Forkhead box protein N3

1

1

High-throughput

0.489

High

274886

LRP5
Low-density lipoprotein receptor-related protein 5

1

4

High-throughput

0.489

High

316617

ST17B
Serine/threonine-protein kinase 17B

1

1

High-throughput

0.489

High

518860

CCL3
C-C motif chemokine 3

1

7

High-throughput

0.489

High

535224

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.489

High

593411

PGFRA
Platelet-derived growth factor receptor alpha

1

7

High-throughput

0.489

High

876261

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

2

High-throughput

0.489

High

1105492

OS9
Protein OS-9

1

4

High-throughput

0.489

High

1124986

RCN2
Reticulocalbin-2

1

7

High-throughput

0.489

High

1177815

CL12B
C-type lectin domain family 12 member B

1

9

High-throughput

0.489

High

1245244

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

7

High-throughput

0.489

High

1258455

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

2

High-throughput

0.489

High

1258463

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

1

High-throughput

0.489

High

1258468

CCPG1
Cell cycle progression protein 1

1

1

High-throughput

0.489

High

1258452

ZNT7
Zinc transporter 7

1

20

High-throughput

0.445

High

218366

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.437

High

410914

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

5

High-throughput

0.437

High

51443

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

4

High-throughput

0.407

High

73825

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

5

High-throughput

0.407

High

170834

CLGN
Calmegin

1

9

High-throughput

0.407

High

458640

PGS2
Decorin

1

6

High-throughput

0.407

High

722503

CTR1
High affinity cationic amino acid transporter 1

1

7

High-throughput

0.407

High

1060361

SLC31
Amino acid transporter heavy chain SLC3A1

1

3

High-throughput

0.407

High

1197805

S39AC
Zinc transporter ZIP12

1

20

High-throughput

0.407

High

1258446

SV2A
Synaptic vesicle glycoprotein 2A

1

2

High-throughput

0.407

High

1258447

SV2B
Synaptic vesicle glycoprotein 2B

1

2

High-throughput

0.407

High

1258448

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

3

High-throughput

0.407

High

1258451

S39AB
Zinc transporter ZIP11

1

20

High-throughput

0.407

High

1258453

S7A14
Solute carrier family 7 member 14

1

7

High-throughput

0.407

High

1258457

S39A7
Zinc transporter SLC39A7

1

20

High-throughput

0.407

High

1258459

S39A8
Metal cation symporter ZIP8

1

20

High-throughput

0.407

High

1258461

SIAE
Sialate O-acetylesterase

2

0

High-throughput

0.318

High

252280

TLR5
Toll-like receptor 5

1

0

High-throughput

0.279

Low

731867

CEAM8
Cell adhesion molecule CEACAM8

1

0

High-throughput

0.279

Low

1258466

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025