HitPredict

Interactor 1: TRAK2 (O60296)
Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein)
Gene: TRAK2

Interactor 2: KLC4 (Q9NSK0)
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)
Gene: KLC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 914 Hs			1 619
+	Hs
		230523 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KLC2_HUMAN (11-619): 1.04e-108: 342: 68.70
+	Hs
		230499 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KLC1_HUMAN (1-544): 7.47e-98: 312: 68.99
+	Hs
		174472 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		OGT1_HUMAN (93-614): 2.89e-49: 186: 15.52
+	Rn
		881492 TRAK2_RAT (1-914): 2.58e-159: 492: 86.56		OGT1_RAT (93-614): 2.81e-49: 186: 15.52
+	Hs
		230507 TRAK2_HUMAN (1-914): 1.13e-170: 521: 100.00		KLC3_HUMAN (290-617): 2.55e-28: 120: 33.33
+	Rn
		70314 HAP1_RAT (95-387): 1.58e-64: 231: 29.10		B2GV74_RAT (1-619): 2.4e-105: 333: 68.88
+	Mm
		193271 HAP1_MOUSE (95-387): 1.41e-62: 225: 27.86		KLC2_MOUSE (1-605): 1.56e-105: 333: 68.09
+	Hs
		1345608 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KLC4_HUMAN (1-619): 4.89e-131: 399: 100.00
+	Mm
		193270 HAP1_MOUSE (95-387): 1.41e-62: 225: 27.86		KLC1_MOUSE (1-541): 1.18e-89: 290: 67.53
+	Hs
		1327451 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KLC2_HUMAN (11-619): 1.04e-108: 342: 68.70
+	Hs
		1202466 HOOK3_HUMAN (62-402): 2.97e-17: 88.9: 16.25		KLC4_HUMAN (1-619): 4.89e-131: 399: 100.00
+	Hs
		1345610 TRAK1_HUMAN (1-237): 9.38e-12: 71: 8.79		KLC4_HUMAN (1-619): 4.89e-131: 399: 100.00
+	Hs
		1307577 AKAP9_HUMAN (39-400): 3.74e-10: 66.5: 16.41		KLC4_HUMAN (1-619): 4.89e-131: 399: 100.00
+	Hs
		992402 HOOK1_HUMAN (62-391): 3.97e-36: 148: 18.21		KLC1_HUMAN (1-544): 7.47e-98: 312: 68.99
+	Hs
		1202456 HOOK3_HUMAN (62-402): 2.97e-17: 88.9: 16.25		KLC2_HUMAN (11-619): 1.04e-108: 342: 68.70
+	Hs
		1327455 TRAK1_HUMAN (1-237): 9.38e-12: 71: 8.79		KLC2_HUMAN (11-619): 1.04e-108: 342: 68.70
+	Hs
		175306 TRAK1_HUMAN (1-237): 9.38e-12: 71: 8.79		OGT1_HUMAN (93-614): 2.89e-49: 186: 15.52
+	Hs
		522556 MYH1_HUMAN (1-606): 2.98e-19: 96.1: 11.13		KLC3_HUMAN (290-617): 2.55e-28: 120: 33.33
+	Hs
		672831 DCTN1_HUMAN (101-551): 8.67e-12: 71.5: 14.47		CDC27_HUMAN (19-369): 1.69e-20: 98.2: 13.20