HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031398 - positive regulation of protein ubiquitination GO:0032991 - protein-containing complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 604
+	Hs
		232150 KDM1A_HUMAN (1-852): 0: 936: 100.00		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		232533 KDM1A_HUMAN (1-852): 0: 936: 100.00		BIRC6_HUMAN (7-136): 3.42e-35: 144: 20.29
+	Hs
		232377 KDM1A_HUMAN (1-852): 0: 936: 100.00		MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60
+	Hs
		1035949 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Dm
		1097136 Q9VF03_DROME (21-301): 3.49e-54: 206: 15.61		DIAP2_DROME (9-100): 4.66e-25: 110: 31.52