HitPredict

Interactor 1: HBP1 (O60381)
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
Gene: HBP1

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	29911972, 15235594
Identification Methods	affinity chromatography technology, two hybrid, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 1273
+	Hs
		1300903 CIC_HUMAN (407-512): 6.93e-40: 156: 33.62		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		1141045 Q60I23_MOUSE (402-511): 1.32e-33: 131: 31.82		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		818379 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		818710 SOX2_MOUSE (402-511): 1.35e-33: 131: 31.82		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		257822 CIC_HUMAN (407-512): 6.93e-40: 156: 33.62		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257753 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257813 BBX_HUMAN (411-512): 3.61e-19: 93.3: 32.04		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15