HitPredict

Interactor 1: HBP1 (O60381)
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
Gene: HBP1

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29911972
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 1048
+	Hs
		1300934 CIC_HUMAN (407-512): 6.93e-40: 156: 33.62		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		727920 SOX6_HUMAN (385-510): 1.46e-36: 146: 30.60		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		727801 SOX5_HUMAN (404-510): 3.14e-35: 142: 31.78		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		818448 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		727910 SOX6_HUMAN (385-510): 1.46e-36: 146: 30.60		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		727788 SOX5_HUMAN (404-510): 3.14e-35: 142: 31.78		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		881826 SOX10_HUMAN (387-512): 9.18e-33: 132: 23.02		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		818837 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		818373 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		818819 SOX9_HUMAN (342-512): 2.12e-32: 131: 19.88		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		1300941 SOX17_HUMAN (381-513): 4.24e-31: 126: 23.02		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		817913 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		MAP1A_HUMAN (7-679): 5.66e-09: 62.8: 8.31
+	Hs
		818266 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		1243837 SOX7_HUMAN (403-513): 3e-31: 126: 26.72		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		1243843 SOX17_HUMAN (381-513): 4.24e-31: 126: 23.02		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		225775 SOX15_HUMAN (390-512): 9.66e-31: 121: 29.84		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76