HitPredict

Interactor 1: EVI5 (O60447)
Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein)
Gene: EVI5

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17229837
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 810 Hs			1 218
+	Hs
		234370 EVI5_HUMAN (1-810): 1.95e-107: 349: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914176 TBCD1_HUMAN (44-534): 2.81e-98: 332: 23.43		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Dm
		185716 EVI5_DROME (76-718): 3.11e-85: 290: 36.68		O18335_DROME (1-216): 4.19e-87: 257: 83.80
+	Hs
		1079952 EVI5L_HUMAN (50-712): 3.39e-76: 265: 68.93		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		914275 EVI5L_HUMAN (50-712): 3.39e-76: 265: 68.93		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		233036 TBC12_HUMAN (13-430): 2.58e-70: 248: 21.57		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		1079972 TBC14_HUMAN (12-423): 1.91e-66: 236: 19.96		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		914423 TBC14_HUMAN (12-423): 1.91e-66: 236: 19.96		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		895106 TB10B_HUMAN (31-450): 1.65e-83: 285: 20.14		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895137 TBCD9_HUMAN (3-487): 4.49e-68: 247: 19.88		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		232698 TBCD4_HUMAN (11-524): 1.94e-66: 243: 22.71		RAB2B_HUMAN (8-178): 1.08e-61: 193: 56.14
+	Hs
		914482 RBGP1_HUMAN (558-808): 1.82e-10: 67: 13.04		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		884622 RBGP1_HUMAN (558-808): 1.82e-10: 67: 13.04		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63