HitPredict

Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_1, PH~SH3_9
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 671 Hs			1 1121
+	Hs
		1153451 PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		235492 VINEX_HUMAN (1-671): 2.64e-132: 406: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1285194 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		298964 SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		596243 NEBU_HUMAN (12-671): 4.58e-53: 200: 12.62		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Mm
		561168 SPTN1_MOUSE (180-622): 2.42e-38: 155: 15.27		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Mm
		82769 B9EKJ1_MOUSE (180-622): 2.42e-38: 155: 15.27		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Hs
		1052250 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		1052323 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		876493 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125453 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		125051 GRAP2_HUMAN (182-436): 9.34e-19: 90.1: 12.83		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		1052316 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		125507 SH319_HUMAN (39-671): 7.07e-13: 73.9: 10.88		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		1074101 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69
+	Hs
		1045520 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		212314 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		CYH3_HUMAN (160-280): 1.5e-27: 118: 27.64
+	Hs
		275221 GRAP2_HUMAN (182-436): 9.34e-19: 90.1: 12.83		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		1056926 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		1078893 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49