Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: APC1 (Q9H1A4)
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)
Gene: ANAPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 25852190, 25482201, 32707033, 20360068
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0051301 - cell division
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 1944
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024