Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B
Interactor 2: APC4 (Q9UJX5)
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Gene: ANAPC4
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25669885, 25673878, 27939943, 28404789, 33961781, 20360068, 24464857, 25750436, 24151075, 26986935, 23007648, 27097363, 31911655, 35271311, 21926987, 21336306, 23160376, 25383541, 23288039 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ANAPC4_WD40~Mad3_BUB1_I |
| Common GO terms | GO:0005634 - nucleus GO:0005680 - anaphase-promoting complex GO:0005829 - cytosol GO:0051301 - cell division |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
