Protein: BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Gene: BNIP3
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q12983

Gene Ontology (top 5):
GO:0000422 - autophagy of mitochondrion
GO:0000423 - mitophagy
GO:0001666 - response to hypoxia
GO:0005634 - nucleus
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

239365

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

13

2

Small-scale

0.987

High

1092041

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

8

2

Small-scale

0.973

High

602210

TMM11
Transmembrane protein 11, mitochondrial

7

1

High-throughput

0.756

High

1092065

PPTC7
Protein phosphatase PTC7 homolog

5

1

High-throughput

0.717

High

1092101

FBXL4
F-box/LRR-repeat protein 4

4

1

Small-scale

0.692

High

1092059

KTN1
Kinectin

3

1

High-throughput

0.675

High

1092072

FATE1
Fetal and adult testis-expressed transcript protein

3

1

High-throughput

0.675

High

1092087

CLC7A
C-type lectin domain family 7 member A

3

1

High-throughput

0.675

High

522085

BCL2
Apoptosis regulator Bcl-2

4

5

Small-scale

0.674

High

1092055

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

3

1

High-throughput

0.616

High

188876

TMPS2
Transmembrane protease serine 2

2

2

High-throughput

0.606

High

437670

HEPS
Serine protease hepsin

2

2

High-throughput

0.606

High

1050015

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

1092006

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

1

High-throughput

0.606

High

1092060

AMGO1
Amphoterin-induced protein 1

2

1

High-throughput

0.606

High

1092073

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

1

High-throughput

0.606

High

1092093

TNMD
Tenomodulin

2

1

High-throughput

0.606

High

1058747

AMPE
Glutamyl aminopeptidase

2

0

High-throughput

0.602

High

1092053

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

2

0

High-throughput

0.602

High

1092097

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.585

High

460257

CD3E
T-cell surface glycoprotein CD3 epsilon chain

2

0

High-throughput

0.580

High

800288

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.580

High

1007426

S35B1
Solute carrier family 35 member B1

2

0

High-throughput

0.580

High

1092043

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.580

High

1092047

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1092049

SC23A
Protein transport protein Sec23A

2

0

High-throughput

0.580

High

1092052

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

1092062

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

1092080

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.580

High

1092082

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

1092083

ZDH15
Palmitoyltransferase ZDHHC15

2

0

High-throughput

0.580

High

1092084

REEP2
Receptor expression-enhancing protein 2

2

0

High-throughput

0.580

High

1092085

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

1092090

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.580

High

1092096

RPRM
Protein reprimo

2

0

High-throughput

0.580

High

1092103

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

1092105

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

245460

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

Small-scale

0.569

High

1092089

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

6

Small-scale

0.561

High

194695

FFAR2
Free fatty acid receptor 2

2

2

High-throughput

0.553

High

1092042

MALL
MAL-like protein

2

1

High-throughput

0.553

High

1092066

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.553

High

1092102

RNF24
RING finger protein 24

2

2

High-throughput

0.553

High

1060160

B2CL1
Bcl-2-like protein 1

1

5

Small-scale

0.552

High

1092048

RHEB
GTP-binding protein Rheb

1

2

Small-scale

0.552

High

186903

GPR37
Prosaposin receptor GPR37

1

1

High-throughput

0.541

High

835453

5HT2B
5-hydroxytryptamine receptor 2B

1

1

High-throughput

0.541

High

1092064

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.536

High

581016

RAC2
Ras-related C3 botulinum toxin substrate 2

1

0

High-throughput

0.513

High

230310

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.508

High

1092063

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

1

High-throughput

0.489

High

385698

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.481

High

1092071

B2CL2
Bcl-2-like protein 2

1

5

High-throughput

0.481

High

1092100

CLN8
Protein CLN8

1

1

Small-scale

0.481

High

1092050

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

0.480

High

216677

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.479

High

281584

MTX2
Metaxin-2

1

1

High-throughput

0.479

High

347668

BAG3
BAG family molecular chaperone regulator 3

1

1

Small-scale

0.479

High

404021

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

1092044

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

1092068

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1092070

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1092077

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.479

High

1092081

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

1

High-throughput

0.479

High

1092086

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

Small-scale

0.479

High

1092094

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

6

Small-scale

0.479

High

1092099

MTCH1
Mitochondrial carrier homolog 1

1

3

High-throughput

0.479

High

1092106

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.479

High

193410

GPR42
G-protein coupled receptor 42

1

2

High-throughput

0.470

High

586285

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

642545

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.460

High

1066620

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.460

High

1092045

HDAC1
Histone deacetylase 1

1

0

Small-scale

0.458

High

1092046

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1092069

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

Small-scale

0.438

High

1092061

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

139862

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

190558

COPT2
Protein SLC31A2

2

0

High-throughput

0.316

High

338252

CLD9
Claudin-9

2

0

High-throughput

0.316

High

1092051

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1092054

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.316

High

1092056

RNK
Ribonuclease kappa

2

0

High-throughput

0.316

High

1092057

TM205
Transmembrane protein 205

2

0

High-throughput

0.316

High

1092074

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.316

High

1092075

F241B
Protein FAM241B

2

0

High-throughput

0.316

High

1092076

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1092078

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.316

High

1092079

TM101
Transmembrane protein 101

2

0

High-throughput

0.316

High

1092088

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.316

High

1092092

S6A17
Sodium-dependent neutral amino acid transporter SLC6A17

2

0

High-throughput

0.316

High

1092095

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.316

High

1092098

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.316

High

1064707

CD47
Leukocyte surface antigen CD47

1

0

Small-scale

0.288

High

720664

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.282

High

1092067

FAM3C
Protein FAM3C

1

0

High-throughput

0.268

Low

1092091

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.251

Low

1092104

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.238

Low

844765

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

1092058

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025