HitPredict

Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: S11IP (Q8N1F8)
Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1)
Gene: STK11IP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 784 Hs			1 1088
+	Hs
		1073327 TLR1_HUMAN (36-782): 4.08e-96: 318: 28.27		S11IP_HUMAN (1-1088): 0: 1106: 100.00
+	Hs
		120165 TLR4_HUMAN (11-782): 2.16e-83: 285: 22.77		S11IP_HUMAN (1-1088): 0: 1106: 100.00
+	Hs
		237514 TLR2_HUMAN (1-784): 1.1e-125: 396: 100.00		LGR4_HUMAN (98-296): 3.23e-13: 76.3: 27.18
+	At
		99021 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		RGI4_ARATH (1-465): 3.18e-59: 223: 15.31
+	At
		1324076 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		MIK1_ARATH (2-475): 7.88e-57: 216: 17.19
+	At
		1324067 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		FLS2_ARATH (6-499): 2e-53: 206: 14.34
+	At
		249728 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		BAME3_ARATH (50-614): 1.27e-46: 183: 14.55
+	At
		84451 Y4361_ARATH (135-711): 2.18e-51: 196: 12.78		GSO1_ARATH (1-452): 2.19e-59: 225: 15.98
+	At
		84461 SKM1_ARATH (123-663): 3.01e-41: 165: 11.53		GSO1_ARATH (1-452): 2.19e-59: 225: 15.98
+	At
		84737 Y4361_ARATH (135-711): 2.18e-51: 196: 12.78		BAME3_ARATH (50-614): 1.27e-46: 183: 14.55
+	Hs
		179963 TLR3_HUMAN (1-784): 7.57e-85: 290: 17.94		LRC40_HUMAN (165-308): 1.25e-11: 70.9: 25.83
+	At
		221535 Y2317_ARATH (9-416): 2.14e-43: 171: 12.11		BAME3_ARATH (50-614): 1.27e-46: 183: 14.55
+	At
		249741 Y1723_ARATH (1-295): 3.75e-42: 168: 15.95		BAME3_ARATH (50-614): 1.27e-46: 183: 14.55
+	At
		1114705 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		ERECT_ARATH (255-502): 5.38e-11: 69: 12.80
+	At
		1167629 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		ERL2_ARATH (255-494): 9.48e-10: 65.2: 13.64
+	At
		85369 FLS2_ARATH (41-694): 3.18e-68: 247: 12.48		ERL1_ARATH (255-494): 7.59e-10: 65.2: 11.93
+	At
		1338062 EMS1_ARATH (1-284): 2e-44: 175: 15.62		RGI1_ARATH (115-593): 2.7e-29: 128: 12.78
+	At
		84728 Y4361_ARATH (135-711): 2.18e-51: 196: 12.78		ERL1_ARATH (255-494): 7.59e-10: 65.2: 11.93
+	At
		1114712 EMS1_ARATH (1-284): 2e-44: 175: 15.62		ERECT_ARATH (255-502): 5.38e-11: 69: 12.80
+	At
		1323635 EMS1_ARATH (1-284): 2e-44: 175: 15.62		GSO2_ARATH (1-56): 2.48e-10: 67.1: 8.93