HitPredict

Interactor 1: MAD3 (O59767)
Mitotic spindle checkpoint component mad3
Gene: MAD3

Interactor 2: BUB1 (O94751)
Spindle assembly checkpoint serine/threonine-protein kinase bub1 (EC 2.7.11.1) (Checkpoint serine/threonine-protein kinase bub1)
Gene: BUB1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 28366743, 26771498, 27618268, 31257143, 23695164
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Mad3_BUB1_I~Mad3_BUB1_I
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0051301 - cell division
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 310
Sp

1 1044
+ Sp
+ Sc
+ Mm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Dm
+ Zm

Service provided by Combinatics, Japan

Last updated: 11Aug2025