Protein: MAD3
Spindle assembly checkpoint component MAD3 (Mitotic MAD3 protein)

Gene: MAD3
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P47074

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0032837 - distributive segregation
GO:0033597 - mitotic checkpoint complex
GO:0044774 - mitotic DNA integrity checkpoint signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686919

BUB3
Spindle assembly checkpoint protein BUB3

9

10

Small-scale

0.978

High

684630

CDC20
APC/C activator protein CDC20

12

11

Small-scale

0.761

High

829801

MAD2
Mitotic spindle checkpoint component MAD2

4

7

Small-scale

0.683

High

460736

CDC4
Cell division control protein 4

1

1

Small-scale

0.618

High

835508

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

1

11

Small-scale

0.618

High

864878

MAD3
Spindle assembly checkpoint component MAD3

1

10

Small-scale

0.618

High

561255

CG13
G1/S-specific cyclin CLN3

2

2

Small-scale

0.600

High

808644

AURK
Aurora kinase

1

2

Small-scale

0.501

High

733547

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.486

High

864880

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.486

High

364617

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.481

High

864882

APC1
Anaphase-promoting complex subunit 1

1

2

High-throughput

0.481

High

486237

TBA1
Tubulin alpha-1 chain

1

1

Small-scale

0.479

High

486485

TBA3
Tubulin alpha-3 chain

1

1

Small-scale

0.479

High

486782

CDC16
Anaphase-promoting complex subunit CDC16

1

9

Small-scale

0.479

High

760294

BMH2
Protein BMH2

1

1

Small-scale

0.479

High

795748

STU1
Protein STU1

1

1

Small-scale

0.479

High

806971

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

5

Small-scale

0.479

High

864881

DAM1
DASH complex subunit DAM1

1

1

Small-scale

0.479

High

864887

SCM3
Protein SCM3

1

0

High-throughput

0.460

High

675295

DMC1
Meiotic recombination protein DMC1

1

0

Small-scale

0.458

High

707511

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

757839

PP2C3
Protein phosphatase 2C homolog 3

1

0

Small-scale

0.458

High

834781

ERG10
Acetyl-CoA acetyltransferase

1

0

Small-scale

0.458

High

864884

CFT1
Protein CFT1

1

0

Small-scale

0.458

High

864886

SLK19
Kinetochore protein SLK19

1

0

Small-scale

0.458

High

545404

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

734522

MSB2
Signaling mucin MSB2

1

0

High-throughput

0.265

Low

386769

TBB
Tubulin beta chain

1

0

Small-scale

0.249

Low

453174

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

Small-scale

0.249

Low

626797

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.249

Low

804814

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

Small-scale

0.249

Low

823431

MPM1
Mitochondrial peculiar membrane protein 1

1

0

Small-scale

0.249

Low

864151

MTC1
Maintenance of telomere capping protein 1

1

0

Small-scale

0.249

Low

864879

RL38
Large ribosomal subunit protein eL38

1

0

Small-scale

0.249

Low

864883

DNM1
Dynamin-related protein DNM1

1

0

Small-scale

0.249

Low

864885

CDA1
Chitin deacetylase 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025