HitPredict

Interactor 1: JAK2 (O60674)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2

Interactor 2: MUC7 (Q8TAX7)
Mucin-7 (MUC-7) (Apo-MG2) (Salivary mucin-7)
Gene: MUC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 377
+	Hs
		166023 ABL1_HUMAN (821-1131): 3.47e-94: 328: 32.05		SYNJ2_HUMAN (100-368): 9.15e-19: 90.2: 16.84
+	Hs
		412433 FYN_HUMAN (817-1125): 1.98e-96: 319: 28.07		MYO16_HUMAN (12-306): 4.05e-21: 97.5: 13.61
+	Hs
		166024 FYN_HUMAN (817-1125): 1.98e-96: 319: 28.07		SYNJ2_HUMAN (100-368): 9.15e-19: 90.2: 16.84
+	Hs
		203198 LCK_HUMAN (801-1132): 4.46e-98: 322: 29.13		SYNJ1_HUMAN (33-376): 1.05e-12: 71.7: 13.33
+	Hs
		337335 ABL1_HUMAN (821-1131): 3.47e-94: 328: 32.05		MUC1_HUMAN (78-374): 9.29e-11: 65.5: 14.14
+	Hs
		522749 SRC_HUMAN (820-1131): 6.64e-99: 326: 25.88		MUC1_HUMAN (78-374): 9.29e-11: 65.5: 14.14
+	Hs
		411582 LCK_HUMAN (801-1132): 4.46e-98: 322: 29.13		MUC1_HUMAN (78-374): 9.29e-11: 65.5: 14.14
+	Hs
		297808 LYN_HUMAN (793-1132): 2.7e-93: 309: 29.91		K0754_HUMAN (18-206): 5.2e-13: 72.9: 12.62
+	Hs
		433560 LYN_HUMAN (793-1132): 2.7e-93: 309: 29.91		MUC1_HUMAN (78-374): 9.29e-11: 65.5: 14.14
+	Hs
		302238 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		SC31A_HUMAN (23-376): 7.13e-29: 120: 15.86
+	Hs
		384551 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		SC24C_HUMAN (43-337): 1.02e-20: 96: 15.51
+	Hs
		302247 FGFR1_HUMAN (545-838): 5.95e-13: 75.5: 22.57		SC31A_HUMAN (23-376): 7.13e-29: 120: 15.86
+	Hs
		297846 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		SC24D_HUMAN (82-369): 1.85e-18: 89.4: 15.20
+	Mm
		222871 ACK1_MOUSE (520-822): 7.53e-17: 88.2: 26.83		MICA3_MOUSE (64-371): 2.58e-18: 89: 12.78
+	Hs
		385252 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		TITIN_HUMAN (78-346): 1.93e-11: 68.2: 14.55
+	Hs
		384286 NTRK1_HUMAN (526-808): 1.64e-20: 99.8: 24.59		RPB1_HUMAN (80-183): 5.13e-09: 60.1: 20.91
+	Hs
		554307 ERBB4_HUMAN (521-808): 2.52e-18: 93.2: 25.25		MUC1_HUMAN (78-374): 9.29e-11: 65.5: 14.14
+	Hs
		203204 FGFR1_HUMAN (545-838): 5.95e-13: 75.5: 22.57		SYNJ1_HUMAN (33-376): 1.05e-12: 71.7: 13.33