HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: NFIA (Q12857)
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)
Gene: NFIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1454 Hs			1 509
+	Hs
		239575 MED14_HUMAN (1-1454): 0: 1569: 100.00		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		239525 MED14_HUMAN (1-1454): 0: 1569: 100.00		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		142737 MED14_HUMAN (1-1454): 0: 1569: 100.00		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		130314 MED14_HUMAN (1-1454): 0: 1569: 100.00		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76
+	Hs
		1088135 CABIN_HUMAN (969-1229): 1.67e-25: 117: 15.39		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1133766 CABIN_HUMAN (969-1229): 1.67e-25: 117: 15.39		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		1087908 CBP_HUMAN (989-1449): 2.12e-14: 81.1: 13.58		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1087875 KMT2C_HUMAN (1122-1454): 2.89e-10: 67.7: 12.68		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1133571 CBP_HUMAN (989-1449): 2.12e-14: 81.1: 13.58		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		1133484 SRCAP_HUMAN (859-1451): 4.65e-12: 73.4: 11.98		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		1133540 KMT2C_HUMAN (1122-1454): 2.89e-10: 67.7: 12.68		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		474412 CABIN_HUMAN (969-1229): 1.67e-25: 117: 15.39		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		143359 CABIN_HUMAN (969-1229): 1.67e-25: 117: 15.39		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		474170 CBP_HUMAN (989-1449): 2.12e-14: 81.1: 13.58		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		143157 CBP_HUMAN (989-1449): 2.12e-14: 81.1: 13.58		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		474133 KMT2C_HUMAN (1122-1454): 2.89e-10: 67.7: 12.68		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		143124 KMT2C_HUMAN (1122-1454): 2.89e-10: 67.7: 12.68		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		319080 SC24D_HUMAN (986-1164): 5.59e-10: 66.4: 18.79		SC31A_HUMAN (222-499): 9.06e-21: 98.4: 12.06
+	Dm
		119660 M9PB30_DROME (896-1454): 3.14e-12: 74.2: 9.78		M9PB30_DROME (182-505): 9.65e-09: 60.3: 12.39
+	Dm
		1485978 CANB_DROME (1004-1196): 1.4e-10: 68.3: 23.27		CANB_DROME (237-427): 1.32e-09: 63: 11.28