Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: SCN9A (Q15858)
Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)
Gene: SCN9A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 37207277
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~cNMP_binding, Ion_trans~Ion_trans, Ion_trans~Ion_trans_N
Common GO terms GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0019228 - neuronal action potential
GO:0030424 - axon
GO:0035725 - sodium ion transmembrane transport
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 890
Hs

1 1988
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024