HitPredict

Interactor 1: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 293 Hs			1 499
+	Hs
		241282 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		432604 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		71086 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		71245 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05
+	Hs
		432605 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		432550 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		432699 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		833938 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833788 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		415100 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		1044256 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		834087 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		833857 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833706 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834017 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		625590 RBM4_HUMAN (17-92): 1e-16: 81.1: 19.74		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		1043996 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	At
		51039 RSZ33_ARATH (8-109): 2.92e-18: 84.6: 21.57		A1L4Y9_ARATH (118-481): 7.46e-116: 348: 42.67
+	At
		847177 RSZ33_ARATH (8-109): 2.92e-18: 84.6: 21.57		AFC3_ARATH (118-481): 7.46e-116: 348: 42.67
+	Hs
		925032 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50