HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21907836
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 240
+	Hs
		850890 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00
+	Hs
		850932 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00
+	Hs
		855491 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		855449 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		855488 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		1087155 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94
+	Hs
		918404 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94
+	Hs
		1087480 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Hs
		918769 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Hs
		1087385 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74
+	Hs
		265986 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60
+	Hs
		266023 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60
+	Hs
		266045 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60
+	Hs
		918663 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74
+	Hs
		707738 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74
+	Hs
		331768 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18
+	Hs
		331825 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18
+	Hs
		707641 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		ZMY11_HUMAN (4-230): 1.65e-33: 129: 15.65
+	Hs
		1190696 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57
+	Hs
		918474 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57