HitPredict

Interactor 1: DIAP2 (O60879)
Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2)
Gene: DIAPH2

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005884 - actin filament
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1101 Hs			1 205
+	Hs
		1330940 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		564704 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		951386 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		925658 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		894489 DIAP3_HUMAN (13-1093): 0: 886: 56.56		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		900958 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		545645 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		892621 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		916010 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		436532 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		925531 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		894328 FMNL2_HUMAN (91-1091): 0: 651: 22.60		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		900815 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		915901 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		894190 FMNL3_HUMAN (91-1091): 0: 642: 21.57		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		436466 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		900661 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		545484 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Dd
		710114 FORH_DICDI (72-1074): 0: 606: 20.76		RAC1A_DICDI (10-204): 4.13e-79: 236: 59.49
+	Dm
		776921 FRL_DROME (192-1093): 0: 586: 21.41		RAC1_DROME (10-195): 1.67e-76: 229: 63.98