HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 1620
+	Hs
		243261 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		666634 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		243277 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		243254 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		243262 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		507875 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411313 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435551 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		609471 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		508145 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Mm
		1142038 DNJA3_MOUSE (2-395): 4.22e-117: 351: 25.98		MUSK_MOUSE (983-1391): 3.56e-116: 390: 30.56
+	Hs
		411469 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435729 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		243251 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		243425 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		384352 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		681463 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Dm
		448256 Q9VFV9_DROME (4-408): 3.25e-132: 387: 47.90		INSR_DROME (1090-1384): 2.39e-63: 241: 39.03
+	Hs
		385330 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081563 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03