HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 156
+	Hs
		244920 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CSTFT_HUMAN (31-148): 4.06e-35: 129: 24.37
+	Hs
		244009 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CSTF2_HUMAN (31-148): 1.11e-34: 128: 23.53
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		244491 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49
+	Hs
		245064 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PUF60_HUMAN (30-113): 1.88e-17: 80.1: 30.95
+	Hs
		244287 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RBM3_HUMAN (42-116): 2.8e-18: 78.1: 36.00
+	Hs
		244481 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SF3B4_HUMAN (30-116): 8.18e-11: 60.8: 23.86
+	Sc
		975986 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48
+	Sc
		860456 RSC1_YEAST (87-841): 2.12e-39: 161: 12.50		HSH49_YEAST (37-113): 2.85e-25: 97.8: 37.18
+	Hs
		319190 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		CIRBP_HUMAN (42-126): 4.4e-21: 85.9: 36.47
+	Rn
		78192 Q6AYL3_RAT (336-590): 5.88e-18: 88.6: 22.75		ELAV1_RAT (7-125): 1.85e-24: 98: 19.01