HitPredict

Interactor 1: O62602 (O62602)
mitogen-activated protein kinase kinase (EC 2.7.12.2)
Gene: lic

Interactor 2: SIMA (Q24167)
Protein similar
Gene: SIMA

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27626673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 334 Dm			1 1507
+	Dm
		247468 O61444_DROME (35-330): 3.53e-110: 328: 53.49		SIMA_DROME (1-1507): 0: 1033: 100.00
+	Dm
		1096510 Q9VEN3_DROME (46-323): 2.92e-99: 307: 31.54		SIMA_DROME (1-1507): 0: 1033: 100.00
+	Hs
		681876 AKT1_HUMAN (20-332): 3.91e-125: 368: 21.25		HIF1A_HUMAN (59-836): 2.5e-117: 391: 25.31
+	Hs
		805431 MP2K3_HUMAN (2-325): 1.74e-116: 341: 60.62		HIF1A_HUMAN (59-836): 2.5e-117: 391: 25.31
+	Hs
		649042 AKT1_HUMAN (20-332): 3.91e-125: 368: 21.25		ARNT_HUMAN (51-710): 3.52e-92: 319: 15.43
+	Hs
		649064 MP2K3_HUMAN (2-325): 1.74e-116: 341: 60.62		ARNT_HUMAN (51-710): 3.52e-92: 319: 15.43
+	Hs
		728975 STK24_HUMAN (29-325): 1.38e-105: 317: 30.90		AHR_HUMAN (52-844): 2.77e-99: 341: 16.14
+	Dm
		1096079 AKT1_DROME (23-332): 7.52e-122: 364: 20.19		TRH_DROME (33-886): 7.98e-77: 279: 17.85
+	Hs
		153165 MP2K7_HUMAN (26-325): 7.95e-106: 317: 43.71		NPAS1_HUMAN (44-539): 2.33e-90: 308: 24.62
+	Hs
		1306169 STK26_HUMAN (46-323): 2.83e-102: 308: 31.18		NPAS1_HUMAN (44-539): 2.33e-90: 308: 24.62
+	Hs
		1026813 MP2K5_HUMAN (52-326): 2.68e-59: 198: 42.76		HIF1A_HUMAN (59-836): 2.5e-117: 391: 25.31
+	Hs
		649095 MP2K5_HUMAN (52-326): 2.68e-59: 198: 42.76		ARNT_HUMAN (51-710): 3.52e-92: 319: 15.43
+	Hs
		735002 MP2K2_HUMAN (40-327): 1.98e-53: 182: 32.93		NPAS1_HUMAN (44-539): 2.33e-90: 308: 24.62