HitPredict

Interactor 1: PRP16 (P15938)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13)
Gene: PRP16

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20089683
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1071 Sc			1 687
+	Sc
		589465 PRP2_YEAST (128-984): 0: 856: 36.20		CLF1_YEAST (1-687): 7.93e-126: 390: 100.00
+	Hs
		1055473 DHX8_HUMAN (65-1013): 0: 780: 36.47		CRNL1_HUMAN (5-685): 4.45e-115: 367: 36.61
+	Sc
		554246 PRP16_YEAST (1-1071): 0: 901: 100.00		SYF1_YEAST (54-674): 1.42e-57: 211: 11.97
+	Sc
		622351 PRP22_YEAST (118-1020): 0: 689: 36.83		CLF1_YEAST (1-687): 7.93e-126: 390: 100.00
+	Sc
		589452 PRP2_YEAST (128-984): 0: 856: 36.20		SYF1_YEAST (54-674): 1.42e-57: 211: 11.97
+	Sc
		859463 PRP43_YEAST (257-1011): 0: 671: 39.79		CLF1_YEAST (1-687): 7.93e-126: 390: 100.00
+	Sp
		194928 DHX15_SCHPO (281-995): 0: 683: 40.63		CLF1_SCHPO (5-686): 5.61e-121: 377: 39.21
+	Hs
		1160938 DHX40_HUMAN (351-1052): 0: 843: 36.41		CTR9_HUMAN (9-434): 5.17e-19: 94.2: 8.39
+	Hs
		1057967 DHX40_HUMAN (351-1052): 0: 843: 36.41		RRP5_HUMAN (376-677): 7.52e-17: 87.3: 13.58
+	Sc
		586358 PRP2_YEAST (128-984): 0: 856: 36.20		PRP6_YEAST (28-198): 6.71e-10: 64.6: 13.30
+	Sc
		622340 PRP22_YEAST (118-1020): 0: 689: 36.83		SYF1_YEAST (54-674): 1.42e-57: 211: 11.97
+	Hs
		1055483 DHX8_HUMAN (65-1013): 0: 780: 36.47		SYF1_HUMAN (2-495): 4.59e-26: 116: 14.67
+	Hs
		1055399 DHX8_HUMAN (65-1013): 0: 780: 36.47		CTR9_HUMAN (9-434): 5.17e-19: 94.2: 8.39
+	Hs
		174828 DHX9_HUMAN (29-1064): 0: 703: 21.29		OGT1_HUMAN (3-340): 4.64e-40: 160: 14.12
+	Hs
		300141 DHX8_HUMAN (65-1013): 0: 780: 36.47		PRP6_HUMAN (449-672): 5e-10: 64.9: 11.89
+	Hs
		224847 DHX16_HUMAN (113-1007): 0: 716: 36.77		SYF1_HUMAN (2-495): 4.59e-26: 116: 14.67
+	Sc
		859429 PRP43_YEAST (257-1011): 0: 671: 39.79		RRP5_YEAST (335-642): 1.55e-24: 111: 14.56
+	Hs
		994172 DHX9_HUMAN (29-1064): 0: 703: 21.29		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08
+	Hs
		1063230 DHX57_HUMAN (29-1064): 0: 635: 21.23		SART3_HUMAN (21-387): 2.31e-11: 69.2: 15.08