HitPredict

Interactor 1: BRL2 (O74563)
E3 ubiquitin-protein ligase brl2 (EC 2.3.2.27) (BRE1-like protein 2) (RING finger protein 1) (RING-type E3 ubiquitin transferase brl2)
Gene: BRL2

Interactor 2: UBC2 (P23566)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (RAD6 homolog) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: rhp6

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 17374714, 17363370
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4_2
Common GO terms GO:0005634 - nucleus
GO:0033503 - HULC complex
GO:0040029 - epigenetic regulation of gene expression
GO:0140673 - transcription elongation-coupled chromatin remodeling
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 680
Sp

1 151
+ At
+ At
+ Sc
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ At
+ Ce
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024