HitPredict

Interactor 1: SRGP2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
Gene: SRGAP2

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 248
+	Mm
		910322 SRGP2_MOUSE (1-1071): 0: 700: 98.23		1433E_MOUSE (2-246): 4.41e-146: 410: 60.41
+	Hs
		253335 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		253338 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		909743 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		253315 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		253321 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Mm
		910285 SRGP3_MOUSE (1-1056): 0: 581: 56.80		1433E_MOUSE (2-246): 4.41e-146: 410: 60.41
+	Hs
		253334 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		927226 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		253342 SRGP2_HUMAN (1-1071): 0: 698: 100.00		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		200215 SRGP3_HUMAN (1-1056): 0: 586: 56.98		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		647054 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		683497 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		904781 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		982210 SRGP1_HUMAN (1-1071): 0: 602: 65.19		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		64663 RHG32_HUMAN (378-1068): 4.17e-83: 299: 17.14		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		927109 RHG29_HUMAN (20-1041): 7.19e-98: 339: 15.37		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		904647 RHG29_HUMAN (20-1041): 7.19e-98: 339: 15.37		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		64657 RHG32_HUMAN (378-1068): 4.17e-83: 299: 17.14		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		64662 RHG32_HUMAN (378-1068): 4.17e-83: 299: 17.14		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62