HitPredict

Interactor 1: WDR1 (O75083)
WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)
Gene: WDR1

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0051015 - actin filament binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 2647
+	Hs
		598240 POC1B_HUMAN (13-226): 6.23e-63: 216: 20.00		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		597996 LIS1_HUMAN (356-605): 1.22e-38: 148: 15.07		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598260 FBXW7_HUMAN (262-604): 2.81e-33: 137: 16.91		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598209 WDR5B_HUMAN (475-604): 3.35e-30: 123: 21.37		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598345 NLE1_HUMAN (1-85): 3.88e-19: 92.7: 18.18		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598040 WDR5_HUMAN (524-605): 2.2e-17: 85.4: 25.30		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		261236 WDR5_HUMAN (524-605): 2.2e-17: 85.4: 25.30		FLNB_HUMAN (28-2647): 0: 2710: 69.63
+	Hs
		903137 WDR5_HUMAN (524-605): 2.2e-17: 85.4: 25.30		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		957555 FBXW7_HUMAN (262-604): 2.81e-33: 137: 16.91		PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81