Interactor 1: FZD7 (O75084)
Frizzled-7 (Fz-7) (hFz7) (FzE3)
Gene: FZD7

Interactor 2: WNT3 (P56703)
Proto-oncogene Wnt-3 (Proto-oncogene Int-4 homolog)
Gene: WNT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 21314951, 18313787
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fz~wnt
Common GO terms GO:0005109 - frizzled binding
GO:0005886 - plasma membrane
GO:0030182 - neuron differentiation
GO:0060070 - canonical Wnt signaling pathway
GO:0071300 - cellular response to retinoic acid
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 574
Hs

1 355
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+ Gg
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+ Hs
+ Mm
+ Hs
+ Mm
+ Gg
+ Mm
+ Mm
+ Hs
+ Mm
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+ Dm
+ Dm
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+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024