HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: PA24D (Q86XP0)
Cytosolic phospholipase A2 delta (cPLA2-delta) (EC 3.1.1.4) (Phospholipase A2 group IVD)
Gene: PLA2G4D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 818
+	Hs
		255175 HCN1_HUMAN (1-890): 0: 680: 100.00		NED4L_HUMAN (8-694): 3.71e-143: 448: 14.34
+	Hs
		131609 HCN1_HUMAN (1-890): 0: 680: 100.00		WWP2_HUMAN (113-687): 2.39e-87: 297: 9.82
+	Hs
		1086476 KCNH2_HUMAN (3-879): 4.49e-158: 495: 18.00		NED4L_HUMAN (8-694): 3.71e-143: 448: 14.34
+	Hs
		136163 HCN1_HUMAN (1-890): 0: 680: 100.00		SYT5_HUMAN (12-285): 2.92e-66: 227: 18.71
+	Hs
		255127 HCN1_HUMAN (1-890): 0: 680: 100.00		SYT2_HUMAN (136-298): 3.15e-22: 102: 14.55
+	Hs
		254805 HCN1_HUMAN (1-890): 0: 680: 100.00		SYT1_HUMAN (136-298): 3.66e-20: 96.1: 13.94
+	Hs
		220648 HCN1_HUMAN (1-890): 0: 680: 100.00		SYT7_HUMAN (136-261): 2.72e-18: 90: 12.60