HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1896 Hs			1 2602
+	Hs
		255501 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		234453 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		FLNB_HUMAN (1-2602): 0: 2855: 100.00
+	Mm
		1161055 MYLK_MOUSE (1626-1708): 5.61e-10: 67: 22.35		FLNB_MOUSE (1-2602): 0: 2844: 95.85
+	Hs
		598253 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		255772 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		FLNC_HUMAN (6-2602): 0: 1470: 35.38
+	Hs
		1052877 MYPC3_HUMAN (3-809): 4.94e-60: 229: 12.18		FLNC_HUMAN (6-2602): 0: 1470: 35.38
+	Hs
		255470 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15
+	Hs
		211438 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58
+	Hs
		256153 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69
+	Hs
		234468 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15
+	Hs
		234502 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65
+	Hs
		211436 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58
+	Hs
		234595 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69
+	Hs
		521586 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15
+	Hs
		725681 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61
+	Hs
		211629 TITIN_HUMAN (513-729): 2.01e-09: 65.5: 10.96		ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58
+	Dm
		574825 TITIN_DROME (1-99): 1.34e-09: 65.8: 22.00		ACTN_DROME (9-259): 5.05e-96: 336: 32.55
+	Mm
		250946 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		MACF1_MOUSE (16-239): 1.26e-34: 149: 40.26
+	Dm
		1337379 TITIN_DROME (1-99): 1.34e-09: 65.8: 22.00		FLNA_DROME (2172-2601): 1.6e-61: 237: 26.01
+	Dm
		65342 OBSCN_DROME (655-985): 3.05e-11: 71.2: 8.33		Q9W4Y3_DROME (1136-2158): 3.74e-24: 114: 10.66