HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26841866, 26496610, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 1322
+	Hs
		257782 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Dm
		1137174 Q5U0Y0_DROME (113-262): 1.27e-22: 107: 36.31		Q9VQ58_DROME (4-1041): 9e-37: 153: 15.74
+	Hs
		1056948 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1302451 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MAGE1_HUMAN (599-1076): 3.61e-09: 63.6: 11.34