HitPredict

Interactor 1: GA45B (O75293)
Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118)
Gene: GADD45B

Interactor 2: M3K4 (Q9Y6R4)
Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)
Gene: MAP3K4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

Property	Details
Experiments	28514442, 33961781, 9827804, 16256071
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:1900745 - positive regulation of p38MAPK cascade
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 1608
+	Hs
		309892 GA45G_HUMAN (1-159): 1.77e-76: 226: 54.94		M3K4_HUMAN (1-1608): 0: 2122: 100.00
+	Hs
		622989 GA45A_HUMAN (1-160): 4.86e-76: 225: 55.76		M3K4_HUMAN (1-1608): 0: 2122: 100.00