HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	31239290, 32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1224
+	Hs
		259537 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		COPB2_HUMAN (196-996): 7.29e-62: 231: 13.86
+	Hs
		260614 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		WDR3_HUMAN (303-477): 8.15e-20: 98.2: 8.81
+	Hs
		259720 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		WDR5_HUMAN (520-631): 1.42e-09: 63.1: 10.35
+	Sc
		922110 GCN5_YEAST (140-462): 2.78e-42: 163: 14.41		COPA_YEAST (195-490): 9.95e-54: 207: 13.66
+	Sp
		268353 YK82_SCHPO (49-215): 1.44e-35: 147: 26.35		NLE1_SCHPO (126-509): 2.53e-40: 158: 15.69
+	Dm
		1463919 Q9VTZ1_DROME (336-457): 5.43e-22: 105: 30.89		WDS_DROME (407-617): 1.99e-43: 164: 10.57
+	Sc
		836090 GCN5_YEAST (140-462): 2.78e-42: 163: 14.41		COPB2_YEAST (2-266): 4.7e-18: 92.4: 12.55
+	Hs
		965132 KAT2B_HUMAN (327-456): 5.64e-22: 105: 26.92		WDR5_HUMAN (520-631): 1.42e-09: 63.1: 10.35
+	Hs
		965131 KAT2A_HUMAN (327-456): 1.77e-20: 100: 26.15		WDR5_HUMAN (520-631): 1.42e-09: 63.1: 10.35
+	Mm
		965395 KMT2C_MOUSE (479-1195): 1.16e-10: 68.8: 11.47		WDR5_MOUSE (520-631): 1.42e-09: 63.1: 10.35