HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 915
+	Hs
		259934 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SAFB2_HUMAN (1-906): 1.46e-88: 304: 68.34
+	Hs
		260517 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		MDN1_HUMAN (63-707): 1.61e-64: 239: 11.64
+	Hs
		260085 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		NIPBL_HUMAN (106-890): 1.47e-60: 227: 10.72
+	Hs
		260530 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		SLTM_HUMAN (29-828): 1.64e-50: 195: 30.24
+	Hs
		259360 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		PABP1_HUMAN (258-499): 8e-38: 153: 14.12
+	Hs
		214262 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		MSI1H_HUMAN (300-495): 1e-37: 147: 18.18
+	Hs
		1141173 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		NIPBL_HUMAN (106-890): 1.47e-60: 227: 10.72
+	Hs
		550481 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		PABP1_HUMAN (258-499): 8e-38: 153: 14.12
+	Hs
		214265 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		MSI1H_HUMAN (300-495): 1e-37: 147: 18.18
+	Hs
		214344 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		MSI1H_HUMAN (300-495): 1e-37: 147: 18.18
+	Hs
		211427 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		RFOX2_HUMAN (301-501): 9.21e-31: 127: 21.80