HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: IPO4 (Q8TEX9)
Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)
Gene: IPO4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17353931, 28675297
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 1081
+	Hs
		1167724 TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85		IPO4_HUMAN (1-1081): 0: 568: 100.00
+	Hs
		127228 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		IPO5_HUMAN (2-1081): 0: 568: 19.98
+	Hs
		879826 TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30		IPO4_HUMAN (1-1081): 0: 568: 100.00
+	Hs
		890764 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		IPO4_HUMAN (1-1081): 0: 568: 100.00
+	Hs
		127251 DUS2_HUMAN (2-154): 7.14e-31: 115: 18.71		IPO5_HUMAN (2-1081): 0: 568: 19.98
+	Hs
		1086075 CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29		IPO4_HUMAN (1-1081): 0: 568: 100.00
+	Hs
		1256969 DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32		IPO4_HUMAN (1-1081): 0: 568: 100.00
+	Sp
		251578 FLP1_SCHPO (3-160): 6.58e-39: 140: 21.97		IMB3_SCHPO (3-1076): 4.21e-144: 462: 20.47
+	Sc
		767707 CDC14_YEAST (11-169): 1.4e-37: 137: 22.73		IMB4_YEAST (1-1079): 2.15e-113: 380: 20.96
+	Sc
		687983 CDC14_YEAST (11-169): 1.4e-37: 137: 22.73		IMB3_YEAST (5-1079): 1.04e-109: 369: 17.81
+	Hs
		312225 TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30		IPO7_HUMAN (1-803): 6.37e-90: 313: 12.32
+	Hs
		312229 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		IPO7_HUMAN (1-803): 6.37e-90: 313: 12.32
+	Hs
		155496 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		TNPO2_HUMAN (199-1080): 9.86e-71: 256: 11.72
+	Hs
		312378 DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32		IPO7_HUMAN (1-803): 6.37e-90: 313: 12.32
+	Hs
		879802 TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		890669 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		1060903 DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		246571 MCE1_HUMAN (30-138): 1.05e-09: 58.2: 25.00		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		1273211 DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32		TNPO1_HUMAN (514-1074): 1.02e-22: 107: 12.96