HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 464
+	Hs
		379969 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		260699 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		348103 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		260819 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		MAX_HUMAN (363-463): 2.41e-25: 103: 33.65
+	Hs
		379580 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379457 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		347244 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		345670 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		345765 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346915 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		391610 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		SC24C_HUMAN (17-348): 1.44e-32: 133: 16.29