HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21907836
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 240
+	Hs
		260808 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		261039 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Hs
		260680 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60
+	Hs
		261003 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74
+	Hs
		850992 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00
+	Hs
		261029 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49
+	Hs
		1115591 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94
+	Hs
		260919 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57
+	Hs
		1349695 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Hs
		1190732 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57
+	Hs
		555365 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		855539 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55
+	Hs
		391730 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94
+	Hs
		555690 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Hs
		391965 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59
+	Mm
		650197 H2AX_MOUSE (1-142): 7.49e-66: 206: 60.69		PSIP1_MOUSE (7-239): 3.58e-35: 132: 36.82
+	Hs
		331860 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18
+	Hs
		331703 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18
+	Hs
		555674 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		DNM3B_HUMAN (8-211): 4.18e-31: 122: 14.49
+	Hs
		555526 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HDGR2_HUMAN (7-222): 6.08e-26: 107: 36.57