HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: U3KQK0 (U3KQK0)
Histone H2B
Gene: H2BC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 166
+	Hs
		1349703 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		U3KQK0_HUMAN (1-166): 9.39e-84: 245: 100.00
+	Hs
		260827 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		260901 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B2E_HUMAN (1-126): 3.12e-58: 179: 98.41
+	Hs
		260958 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1H_HUMAN (1-126): 3.64e-58: 179: 98.41
+	Hs
		241398 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		260769 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1B_HUMAN (1-126): 8e-58: 178: 98.41
+	Hs
		260816 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2BFS_HUMAN (1-126): 8.09e-58: 178: 96.83
+	Hs
		260988 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1N_HUMAN (1-126): 1.1e-57: 178: 100.00
+	Hs
		260935 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		260963 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		H2B1A_HUMAN (1-126): 1.49e-49: 157: 85.83
+	Hs
		1087446 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B2E_HUMAN (1-126): 3.12e-58: 179: 98.41
+	Hs
		420890 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B1J_HUMAN (1-126): 3.68e-58: 179: 97.62
+	Hs
		918741 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		1307097 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B1N_HUMAN (1-126): 1.1e-57: 178: 100.00
+	Hs
		241652 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		1231257 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		1282975 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		H2B1A_HUMAN (1-126): 1.49e-49: 157: 85.83
+	Hs
		420800 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		H2B1J_HUMAN (1-126): 3.68e-58: 179: 97.62
+	Hs
		555295 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		H2B1O_HUMAN (1-126): 2.74e-58: 179: 97.62
+	Hs
		241436 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41