Protein: DMB
HLA class II histocompatibility antigen, DM beta chain (MHC class II antigen DMB) (Really interesting new gene 7 protein)

Gene: DMB, HLA-DMB
Organism: Homo sapiens
Interactions: 54
UniProt ID: P28068

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002399 - MHC class II protein complex assembly
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0019886 - antigen processing and presentation of exogenous peptide antigen via MHC class II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380262

DRA
HLA class II histocompatibility antigen, DR alpha chain

4

18

Small-scale

0.895

High

700771

DMA
HLA class II histocompatibility antigen, DM alpha chain

3

18

Small-scale

0.861

High

700790

Q6ICR9
HLA-DMA protein

1

19

Small-scale

0.692

High

193679

TPSN
Tapasin

1

19

High-throughput

0.691

High

380616

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

18

High-throughput

0.691

High

700810

AP3M1
AP-3 complex subunit mu-1

3

2

High-throughput

0.662

High

700774

ACV1B
Activin receptor type-1B

1

1

High-throughput

0.618

High

700782

NKG2E
NKG2-E type II integral membrane protein

1

20

High-throughput

0.618

High

700800

TECT2
Tectonic-2

2

6

High-throughput

0.574

High

170485

RAB7L
Ras-related protein Rab-7L1

1

9

High-throughput

0.536

High

700802

ABCA2
ATP-binding cassette sub-family A member 2

1

4

High-throughput

0.536

High

700805

ABCB6
ATP-binding cassette sub-family B member 6

1

5

High-throughput

0.536

High

700783

CUL3
Cullin-3

1

1

High-throughput

0.494

High

170670

CLGN
Calmegin

1

9

High-throughput

0.489

High

230756

EXTL3
Exostosin-like 3

1

6

High-throughput

0.489

High

249429

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

3

High-throughput

0.489

High

261091

NSMA
Sphingomyelin phosphodiesterase 2

1

3

High-throughput

0.489

High

565564

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

11

High-throughput

0.489

High

698401

CALX
Calnexin

1

9

High-throughput

0.489

High

700776

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.489

High

700777

5HT3A
5-hydroxytryptamine receptor 3A

1

4

High-throughput

0.489

High

700779

S12A2
Solute carrier family 12 member 2

1

2

High-throughput

0.489

High

700785

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.489

High

700786

MKS3
Meckelin

1

4

High-throughput

0.489

High

700787

S27A3
Long-chain fatty acid transport protein 3

1

5

High-throughput

0.489

High

700788

ODR4
Protein odr-4 homolog

1

1

High-throughput

0.489

High

700789

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

3

High-throughput

0.489

High

700792

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

2

High-throughput

0.489

High

700793

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.489

High

700794

VRK2
Serine/threonine-protein kinase VRK2

1

1

High-throughput

0.489

High

700795

S2529
Mitochondrial basic amino acids transporter

1

11

High-throughput

0.489

High

700801

ARL5B
ADP-ribosylation factor-like protein 5B

1

3

High-throughput

0.489

High

700804

SEC12
Guanine nucleotide-exchange factor SEC12

1

1

High-throughput

0.489

High

700806

PYRG2
CTP synthase 2

1

1

High-throughput

0.489

High

700808

UFSP2
Ufm1-specific protease 2

1

1

High-throughput

0.489

High

700809

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.489

High

700812

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

6

High-throughput

0.489

High

477407

CD63
CD63 antigen

1

8

Small-scale

0.479

High

697348

CD82
CD82 antigen

1

8

Small-scale

0.437

High

700811

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.437

High

700798

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

2

0

High-throughput

0.313

High

700773

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.282

High

700781

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.282

High

700775

FDFT
Squalene synthase

1

0

High-throughput

0.279

Low

700780

BI1
Bax inhibitor 1

1

0

High-throughput

0.279

Low

700784

CP51A
Lanosterol 14-alpha demethylase

1

0

High-throughput

0.279

Low

700791

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.279

Low

700796

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.279

Low

700797

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.279

Low

700799

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

700803

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

700807

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.279

Low

700813

TX264
Testis-expressed protein 264

1

0

High-throughput

0.279

Low

700778

PSN2
Presenilin-2

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025