Interactor 1: CDC45 (O75419)
Cell division control protein 45 homolog (PORC-PI-1)
Gene: CDC45

Interactor 2: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 23364835, 16902406
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006268 - DNA unwinding involved in DNA replication
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 566
Hs

1 863
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Sp
+ Sc
+ Sp
+ Sc
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024