Protein: KLF2
Kruppel-like factor 2

Gene: KLF2, klf-2
Organism: Caenorhabditis elegans
Interactions: 85
UniProt ID: O62259

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

113176

SEM4
Spalt-like protein sem-4

1

13

High-throughput

0.656

High

115127

HAM2
Zinc finger protein ham-2

1

17

High-throughput

0.656

High

145352

O01960
C2H2-type domain-containing protein

1

14

High-throughput

0.656

High

145833

O02273
C2H2-type domain-containing protein

1

18

High-throughput

0.656

High

233878

O45494
C2H2-type domain-containing protein

1

17

High-throughput

0.656

High

264169

ZTF30
Zinc finger transcription factor family protein 30

1

20

High-throughput

0.656

High

264184

UNC98
Zinc finger protein unc-98

1

19

High-throughput

0.656

High

264188

Q19807
C2H2-type domain-containing protein

1

18

High-throughput

0.656

High

264191

EGL43
Zinc finger protein egl-43

1

19

High-throughput

0.656

High

264194

PAT9
Zinc finger protein pat-9

1

19

High-throughput

0.656

High

264213

SDZ12
Zinc finger protein sdz-12

1

19

High-throughput

0.656

High

115705

ZTF16
Zinc finger protein ztf-16

1

20

High-throughput

0.590

High

264199

SMA9
Transcription factor sma-9

1

20

High-throughput

0.590

High

264217

LSY2
Zinc finger protein lsy-2

1

19

High-throughput

0.590

High

113762

HIF1
Hypoxia-inducible factor 1

1

9

High-throughput

0.508

High

114021

ELT6
Transcription factor elt-6

1

16

High-throughput

0.508

High

115199

NHR66
Nuclear hormone receptor family member nhr-66

1

20

High-throughput

0.508

High

195785

FOXO
Forkhead box protein O

1

20

High-throughput

0.508

High

196013

NFYB1
Nuclear transcription factor Y subunit nfyb-1

1

3

High-throughput

0.508

High

196287

EYA1
Protein phosphatase eya-1

1

2

High-throughput

0.508

High

196533

HM35
Homeobox protein unc-39

1

4

High-throughput

0.508

High

196819

MAB3
Protein male abnormal 3

1

4

High-throughput

0.508

High

233852

NHR4
Nuclear hormone receptor family member nhr-4

1

20

High-throughput

0.508

High

233922

NH111
Nuclear hormone receptor family member nhr-111

1

20

High-throughput

0.508

High

264167

MEC3
Mechanosensory protein 3

1

9

High-throughput

0.508

High

264168

LIN11
Protein lin-11

1

8

High-throughput

0.508

High

264170

LIN39
Homeobox protein lin-39

1

6

High-throughput

0.508

High

264171

NHR23
Nuclear hormone receptor family member nhr-23

1

20

High-throughput

0.508

High

264172

CNR14
Steroid hormone receptor family member cnr14

1

20

High-throughput

0.508

High

264173

HM09
Homeobox protein ceh-9

1

15

High-throughput

0.508

High

264174

NHR20
Nuclear hormone receptor family member nhr-20

1

20

High-throughput

0.508

High

264175

NHR22
Nuclear hormone receptor family member nhr-22

1

20

High-throughput

0.508

High

264176

SPE44
Transcription regulator spe-44

1

12

High-throughput

0.508

High

264177

NHR31
Nuclear hormone receptor family member nhr-31

1

20

High-throughput

0.508

High

264178

DX39B
Spliceosome RNA helicase DDX39B homolog

1

5

High-throughput

0.508

High

264179

FLH2
FLYWCH transcription factor 2

1

2

High-throughput

0.508

High

264180

HMX
Homeobox protein mls-2

1

19

High-throughput

0.508

High

264181

Q18605
PHD-type domain-containing protein

1

20

High-throughput

0.508

High

264182

Q18624
SAND domain-containing protein

1

12

High-throughput

0.508

High

264185

DMD5
Doublesex- and mab-3-related transcription factor dmd-5

1

4

High-throughput

0.508

High

264186

ZTF2
Zinc finger protein ztf-2

1

19

High-throughput

0.508

High

264187

Q19496
Nuclear Hormone Receptor family

1

20

High-throughput

0.508

High

264190

Q21777
C2H2-type domain-containing protein

1

11

High-throughput

0.508

High

264193

TBX9
T-box transcription factor tbx-9

1

14

High-throughput

0.508

High

264195

HM31
Homeobox protein ceh-31

1

14

High-throughput

0.508

High

264204

Q86MF0
Fork-head domain-containing protein

1

20

High-throughput

0.508

High

264208

Q8MXK0
Nuclear Hormone Receptor family

1

20

High-throughput

0.508

High

264209

SEM2
Transcription factor sem-2

1

18

High-throughput

0.508

High

264211

Q95QB3
Nuclear Hormone Receptor family

1

20

High-throughput

0.508

High

264212

Q95Y07
Nuclear Hormone Receptor family

1

20

High-throughput

0.508

High

264214

Q9GYG1
C2H2-type domain-containing protein

1

1

High-throughput

0.508

High

264215

MKRN
E3 ubiquitin-protein ligase makorin

1

2

High-throughput

0.508

High

264216

UNC62
Homeobox protein unc-62

1

6

High-throughput

0.508

High

264218

NHR5
Nuclear hormone receptor family member nhr-5

1

20

High-throughput

0.508

High

264220

Q9TXN8
DM domain-containing protein

1

4

High-throughput

0.508

High

264222

MOE3
CCCH-type zinc finger protein moe-3

1

1

High-throughput

0.508

High

264223

PHP3
Homeobox protein php-3

1

6

High-throughput

0.508

High

264225

Q9XWS3
MADF domain-containing protein

1

1

High-throughput

0.508

High

264226

NHR8
Nuclear hormone receptor family member nhr-8

1

20

High-throughput

0.508

High

111041

G5ECP6
C2H2-type domain-containing protein

1

0

High-throughput

0.486

High

115023

H2KY76
THAP-type domain-containing protein

1

0

High-throughput

0.486

High

144751

O01527
C2H2-type domain-containing protein

1

0

High-throughput

0.486

High

264196

Q23521
C2H2-type domain-containing protein

1

0

High-throughput

0.486

High

86642

B9WRT8
C3H1-type domain-containing protein

1

1

High-throughput

0.481

High

264197

Q3LQX0
Nuclear Hormone Receptor family

1

20

High-throughput

0.481

High

264200

Q7JP54
NR LBD domain-containing protein

1

20

High-throughput

0.481

High

264201

Q7KX66
Nuclear receptor domain-containing protein

1

20

High-throughput

0.481

High

264203

Q86G95
Transcription factor CBF/NF-Y/archaeal histone domain-containing protein

1

11

High-throughput

0.481

High

264205

Q86PI8
Nuclear receptor NHR-114

1

20

High-throughput

0.481

High

264219

Q9NAE4
BZIP domain-containing protein

1

18

High-throughput

0.464

High

112618

NH114
Nuclear hormone receptor 114

1

20

High-throughput

0.457

High

115437

H2KZA1
Nuclear hormone receptor E75

1

20

High-throughput

0.457

High

116072

H2L0L6
NR LBD domain-containing protein

1

20

High-throughput

0.457

High

145869

O02289
C3H1-type domain-containing protein

1

1

High-throughput

0.457

High

264189

Q20237
Transcription factor CBF/NF-Y/archaeal histone domain-containing protein

1

9

High-throughput

0.457

High

264198

EHN3
Zinc finger protein ehn-3

1

20

High-throughput

0.457

High

264206

Q86PJ4
Nuclear Hormone Receptor family

1

20

High-throughput

0.457

High

264224

FLH1
FLYWCH transcription factor 1

1

2

High-throughput

0.457

High

264202

Q86DC0
SAM domain-containing protein

1

7

High-throughput

0.439

High

264207

Q8I7K9
LIn-26 Related

1

1

High-throughput

0.439

High

109752

G5EBR0
LIR-1A protein

1

1

High-throughput

0.417

High

264183

Q18662
Caskin-2

1

19

High-throughput

0.417

High

264192

MIG5
Segment polarity protein dishevelled homolog mig-5

1

12

High-throughput

0.417

High

264210

Q93520
AAA domain-containing protein

1

0

High-throughput

0.265

Low

264221

Q9U2K7
SNAPc

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025