Interactor 1: KCC2D (O62305)
Calcium/calmodulin-dependent protein kinase type II (CaM kinase II) (EC 2.7.11.17) (Uncoordinated protein 43)
Gene: unc-43
Interactor 2: PMK1 (Q17446)
Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (Stress-activated protein kinase pmk-1) (p38 MAP kinase 1)
Gene: pmk-1
Species: Caenorhabditis elegans
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14704431 |
| Identification Methods | two hybrid, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CaMKII_AD~Pkinase, Pkinase~Pkinase |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression GO:0046872 - metal ion binding and 1 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
