Protein: PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)

Gene: PHKG2
Organism: Homo sapiens
Interactions: 96
UniProt ID: P15735

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004689 - phosphorylase kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585772

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

10

8

High-throughput

0.978

High

585773

KPB1
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform

8

8

High-throughput

0.972

High

585815

KPBB
Phosphorylase b kinase regulatory subunit beta

7

8

High-throughput

0.967

High

302035

SEGN
Secretagogin

3

20

High-throughput

0.861

High

225528

AAKB2
5'-AMP-activated protein kinase subunit beta-2

3

13

High-throughput

0.855

High

585834

AAKB1
5'-AMP-activated protein kinase subunit beta-1

3

12

High-throughput

0.855

High

585809

DOK4
Docking protein 4

3

0

High-throughput

0.816

High

585786

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

2

15

High-throughput

0.811

High

585791

PHKG1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform

2

16

High-throughput

0.811

High

516306

CALM1
Calmodulin-1

2

20

High-throughput

0.712

High

585775

DAPK1
Death-associated protein kinase 1

1

17

High-throughput

0.692

High

171664

GAK
Cyclin-G-associated kinase

1

18

High-throughput

0.691

High

585764

CALL3
Calmodulin-like protein 3

1

20

High-throughput

0.691

High

585771

MK08
Mitogen-activated protein kinase 8

1

15

High-throughput

0.691

High

585784

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

10

High-throughput

0.691

High

585776

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

3

11

High-throughput

0.662

High

585808

CTCFL
Transcriptional repressor CTCFL

1

0

High-throughput

0.656

High

585789

SETB1
Histone-lysine N-methyltransferase SETDB1

2

2

High-throughput

0.628

High

585793

CE85L
Centrosomal protein of 85 kDa-like

2

1

High-throughput

0.628

High

240661

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.618

High

585766

CDN1A
Cyclin-dependent kinase inhibitor 1

1

3

High-throughput

0.618

High

585779

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.618

High

585782

FOXK1
Forkhead box protein K1

1

3

High-throughput

0.618

High

585787

SNTB2
Beta-2-syntrophin

1

12

High-throughput

0.618

High

585800

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

585822

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.618

High

585805

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

2

High-throughput

0.609

High

585810

ZC3HF
Zinc finger CCCH domain-containing protein 15

2

0

High-throughput

0.602

High

585833

DRG1
Developmentally-regulated GTP-binding protein 1

2

0

High-throughput

0.602

High

516380

CALM2
Calmodulin-2

1

20

High-throughput

0.575

High

516462

CALM3
Calmodulin-3

1

20

High-throughput

0.575

High

342735

HERC2
E3 ubiquitin-protein ligase HERC2

2

9

High-throughput

0.571

High

585769

MAGA2
Melanoma-associated antigen 2

2

7

High-throughput

0.553

High

585774

FAS
Fatty acid synthase

1

1

High-throughput

0.536

High

585778

PSA
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.536

High

585781

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

High-throughput

0.536

High

585785

ACACA
Acetyl-CoA carboxylase 1

1

2

High-throughput

0.536

High

585794

ATD3C
ATPase family AAA domain-containing protein 3C

1

6

High-throughput

0.536

High

585802

CLAP1
CLIP-associating protein 1

1

3

High-throughput

0.536

High

585813

GCN1
Stalled ribosome sensor GCN1

1

4

High-throughput

0.536

High

585814

TNPO1
Transportin-1

1

4

High-throughput

0.536

High

585820

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.536

High

585823

EMAL4
Echinoderm microtubule-associated protein-like 4

1

1

High-throughput

0.536

High

585825

ATD3A
ATPase family AAA domain-containing protein 3A

1

7

High-throughput

0.536

High

585827

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

10

High-throughput

0.536

High

585829

CHIP
E3 ubiquitin-protein ligase CHIP

1

7

High-throughput

0.536

High

585836

5MP1
eIF5-mimic protein 1

1

3

High-throughput

0.536

High

134545

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

270715

N4BP1
NEDD4-binding protein 1

1

0

High-throughput

0.513

High

585765

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.513

High

585767

ADCY8
Adenylate cyclase type 8

1

0

High-throughput

0.513

High

585770

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

0

High-throughput

0.513

High

585788

SNX1
Sorting nexin-1

1

0

High-throughput

0.513

High

585804

CENPV
Centromere protein V

1

0

High-throughput

0.513

High

585807

DDX55
ATP-dependent RNA helicase DDX55

1

0

High-throughput

0.513

High

585831

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

585832

PPR3C
Protein phosphatase 1 regulatory subunit 3C

1

0

High-throughput

0.513

High

228795

SCO2
Protein SCO2 homolog, mitochondrial

1

2

High-throughput

0.489

High

535813

LAMC1
Laminin subunit gamma-1

1

1

High-throughput

0.489

High

585799

F171B
Protein FAM171B

1

2

High-throughput

0.489

High

585819

RN145
RING finger protein 145

1

1

High-throughput

0.489

High

124576

EYA2
Protein phosphatase EYA2

1

1

High-throughput

0.479

High

330632

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

585763

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

585777

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

585783

UBE3A
Ubiquitin-protein ligase E3A

1

11

Small-scale

0.479

High

585790

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

1

High-throughput

0.479

High

585792

DCAF6
DDB1- and CUL4-associated factor 6

1

6

High-throughput

0.479

High

585795

SPD2A
SH3 and PX domain-containing protein 2A

1

3

High-throughput

0.479

High

585796

FBW10
F-box/WD repeat-containing protein 10

1

5

High-throughput

0.479

High

585803

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

High-throughput

0.479

High

585812

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

585817

MYO19
Unconventional myosin-XIX

1

5

High-throughput

0.479

High

585824

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

2

High-throughput

0.479

High

585826

HAUS2
HAUS augmin-like complex subunit 2

1

1

High-throughput

0.479

High

293155

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

413127

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

51038

PKHG3
Pleckstrin homology domain-containing family G member 3

1

9

High-throughput

0.445

High

253550

PEX10
Peroxisome biogenesis factor 10

1

5

High-throughput

0.437

High

585798

H3C
Histone H3.3C

1

9

High-throughput

0.437

High

94363

D6RA89
RING-type E3 ubiquitin transferase

1

1

High-throughput

0.407

High

585780

H31
Histone H3.1

1

9

High-throughput

0.407

High

585811

S39A7
Zinc transporter SLC39A7

1

1

High-throughput

0.407

High

585830

XCT
Cystine/glutamate transporter

1

3

High-throughput

0.407

High

190701

MPPD1
Metallophosphoesterase domain-containing protein 1

3

0

High-throughput

0.347

High

137641

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.279

Low

280485

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.279

Low

585797

ATG9B
Autophagy-related protein 9B

1

0

High-throughput

0.279

Low

585801

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.279

Low

585816

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

0

High-throughput

0.279

Low

585818

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

1

0

High-throughput

0.279

Low

585828

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

585835

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.279

Low

585821

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.249

Low

585768

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

585806

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025