HitPredict

Interactor 1: MTX2 (O75431)
Metaxin-2 (Mitochondrial outer membrane import complex protein 2)
Gene: MTX2

Interactor 2: MTX3 (Q5HYI7)
Metaxin-3
Gene: MTX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 32877691, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GST_C_6~Tom37
Common GO terms	GO:0001401 - SAM complex GO:0005737 - cytoplasm GO:0007005 - mitochondrion organization GO:0007007 - inner mitochondrial membrane organization GO:0140275 - MIB complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 312
+	Hs
		264562 MTX2_HUMAN (1-263): 3.9e-120: 345: 100.00		MTX1_HUMAN (1-303): 6.09e-117: 346: 46.50
+	Hs
		1126150 FAXC_HUMAN (20-257): 1.09e-78: 244: 23.55		MTX3_HUMAN (1-312): 1.45e-123: 357: 100.00
+	Hs
		264576 MTX2_HUMAN (1-263): 3.9e-120: 345: 100.00		FAXC_HUMAN (7-242): 9.61e-74: 234: 21.85
+	Dm
		1367139 Q9VW58_DROME (14-257): 5.97e-89: 266: 44.00		MTX1_DROME (7-262): 6.14e-86: 262: 28.24
+	Dm
		1250338 Q8T4F2_DROME (14-259): 9.59e-82: 248: 36.08		MTX1_DROME (7-262): 6.14e-86: 262: 28.24
+	Hs
		1136806 FAXC_HUMAN (20-257): 1.09e-78: 244: 23.55		FAXC_HUMAN (7-242): 9.61e-74: 234: 21.85